Speakers

Jason Stein, PhD

Associate Professor, Genetics and Neuroscience Center at the UNC School of Medicine

Jason Stein is an associate professor in the Department of Genetics and the Neuroscience Center at the University of North Carolina at Chapel Hill. He is Principal Investigator of the Stein Lab, which explores how variations in the genome change the structure and development of the brain, and in doing so, create risk for neuropsychiatric disorders. He received a BA from Northwestern University in the Integrated Science Program and then pursued post-baccalaureate work at the intramural program of the National Institute of Mental Health with Andreas Meyer-Lindenberg. He received his PhD in Neuroscience from the University of California, Los Angeles under Paul Thompson, where he worked on discovering the genetic influences on macroscale human brain structure. He also completed post-doctoral training at the University of California, Los Angeles under Dan Geschwind where he developed tools to evaluate how well neural stem cells model brain development and studied regulatory regions governing human neurogenesis. 

Robyn Tanguay, PhD

Professor, Department of Environmental and Molecular Toxicology at Oregon State University 

Robyn Leigh Tanguay (Formerly Robert Leonard Tanguay) is a Distinguished Professor in the Department of Environmental and Molecular Toxicology, the Director of the Oregon State University Superfund Research Program, Director of the Sinnhuber Aquatic Research Laboratory, and the Director of an Environmental Health Sciences Center. She received her BA in Biology from California State University-San Bernardino, her PhD in Biochemistry from the University of California-Riverside, and postdoctoral training in Developmental Toxicology from the University of Wisconsin-Madison. She serves on a number of academic, commercial, and federal advisory boards and is on the editorial board for several scientific journals. Over the past several years she has pioneered the use of zebrafish as a toxicology model and recently developed automated high throughput instrumentation to accelerate phenotype discovery in zebrafish. A major focus is on identifying chemicals and mixtures that produce neurotoxicity. Phenotypic anchoring coupled with the inherent molecular and genetic advantages of zebrafish is used to define the mechanisms by which chemicals, drugs, and nanoparticles interact with and adversely affect vertebrate development and function.

Abstract

Transform manual workflows into automated, AI-powered assays. Join early Ramona users Jason Stein, PhD, and Robyn Tanguay, PhD, as they share how to leverage high-throughput imaging and AI-enabled analysis to rapidly screen organoids and zebrafish in well plates. 

Dr. Stein, an Associate Professor at UNC-Chapel Hill and Principal Investigator of the Stein Lab, utilizes Ramona’s Vireo to image and analyze iPSC-derived cortical organoids. Dr. Tanguay, a Distinguished Professor at Oregon State University and Director of multiple research programs, applies Ramona’s Kestrel to study zebrafish behavior and movement. 

Key takeaways: 

• Leverage automation to streamline workflows 

• Gain insights from AI-enabled analysis for accuracy 

• Explore real-world applications for organoid and zebrafish research